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1

Novel interactions of perlecan: Unraveling perlecan's role in angiogenesis

Gregory Bix, Renato V. Iozzo

Journal:

Microscopy Research and Technique

Year:

2008

Language:

english

File:

PDF, 513 KB

english, 2008

2

Bilateral carotid artery stenosis causes unexpected early changes in brain extracellular matrix and blood-brain barrier integrity in mice

Roberts, Jill M., Maniskas, Michael E., Bix, Gregory J., Deli, Mária A.

Journal:

Year:

2018

Language:

english

File:

PDF, 11.70 MB

english, 2018

3

Neurogenesis After Stroke: A Therapeutic Perspective

Rahman, Abir A., Amruta, Narayanappa, Pinteaux, Emmanuel, Bix, Gregory J.

Journal:

Translational Stroke Research

Year:

2020

File:

PDF, 735 KB

2020

4

Perlecan domain V modulates astrogliosis In vitro and after focal cerebral ischemia through multiple receptors and increased nerve growth factor release

Abraham J. Al-Ahmad, Boyeon Lee, Maxim Saini, Gregory J. Bix

Journal:

Year:

2011

Language:

english

File:

PDF, 2.62 MB

english, 2011

5

Elvax as a slow-release delivery agent for a platelet-activating factor receptor agonist and antagonist

Gregory J Bix, Gary D Clark

Journal:

Journal of Neuroscience Methods

Year:

1997

Language:

english

File:

PDF, 162 KB

english, 1997

6

Oxygen–glucose deprivation and interleukin-1α trigger the release of perlecan LG3 by cells of neurovascular unit

Maxim G. Saini, Emmanuel Pinteaux, Boyeon Lee, Gregory J. Bix

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 713 KB

english, 2011

7

10.1038/1221

Wynshaw-Boris, Anthony, Hirotsune, Shinji, Fleck, Mark W., Gambello, Michael J., Bix, Gregory J., Chen, Amy, Clark, Gary D., Ledbetter, David H., McBain, Chris J.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 629 KB

english, 1998

8

Neuronal Platelet-Activating Factor Receptor Signal Transduction Involves a Pertussis Toxin-Sensitive G-Protein

Gary D. Clark, Charles F. Zorumski, Robert S. McNeil, Leo T. Happel, Ty Ovella, Shannon McGuire, Gregory J. Bix, John W. Swann

Journal:

Neurochemical Research

Year:

2000

Language:

english

File:

PDF, 75 KB

english, 2000

9

Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro

Abraham Al Ahmad, Boyeon Lee, Jonathan Stack, Christi Parham, Joel Campbell, Douglas Clarke, Andrzej Fertala, Gregory J. Bix

Journal:

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

10

Oxygen–glucose deprivation (OGD) and interleukin-1 (IL-1) differentially modulate cathepsin B/L mediated generation of neuroprotective perlecan LG3 by neurons

Maxim G. Saini, Gregory J. Bix

Journal:

Year:

2012

Language:

english

File:

PDF, 988 KB

english, 2012

11

Matrix revolutions: ‘tails’ of basement-membrane components with angiostatic functions

Gregory Bix, Renato V. Iozzo

Journal:

Trends in Cell Biology

Year:

2005

Language:

english

File:

PDF, 435 KB

english, 2005

12

Molecular cloning and expression of the IL-10 gene from guinea pigs

Vijaya R. Dirisala, Amminikutty Jeevan, Gregory Bix, Teizo Yoshimura, David N. McMurray

Journal:

Year:

2012

Language:

english

File:

PDF, 645 KB

english, 2012

13

Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity

Sarah Wright, Christi Parham, Boyeon Lee, Douglas Clarke, Lisa Auckland, Jennifer Johnston, Andrea L. Lawrence, S. Kent Dickeson, Samuel A. Santoro, Irene Griswold-Prenner, Gregory Bix

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.88 MB

english, 2012

14

Perlecan Domain V Is Neuroprotective and Affords Functional Improvement in a Photothrombotic Stroke Model in Young and Aged Mice

Gregory J. Bix, Emma K. Gowing, Andrew N. Clarkson

Journal:

Translational Stroke Research

Year:

2013

Language:

english

File:

PDF, 538 KB

english, 2013

15

Editorial

Bix, Gregory J.

Journal:

Physiology & Behavior

Year:

1985

Language:

english

File:

PDF, 34 KB

english, 1985

16

Perlecan Domain V Inhibits Brain Endothelial Cell Abeta Toxicity in Vitro

Bix, Gregory J.

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 271 KB

english, 2009

17

Perlecan domain V inhibits alpha 2 integrin mediated Abeta neurotoxicity

Bix, Gregory J., Wright, Sarah, Clarke, Douglas, Lee, Boyeon, Auckland, Lisa, Parham, Christi, Johnston, Jennifer, Lawrence, Andrea, Dickerson, S. Kent, Santoro, Samuel, Griswold-Prenner, Irene

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

18

Perlecan's domain V prevents amyloid-beta toxicity

Parham, Christi, Kahle, Michael, Shaw, Courtney, Auckland, Lisa, Griswold-Prenner, Irene, Bix, Gregory

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

19

Perlecan Domain V Therapy for Stroke: A Beacon of Hope?

Journal:

ACS Chemical Neuroscience

Year:

2013

Language:

english

File:

PDF, 614 KB

english, 2013

20

Selective intra-arterial drug administration in a model of large vessel ischemia

Maniskas, Michael, Bix, Gregory, Fraser, Justin

Journal:

Journal of Neuroscience Methods

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

21

Understanding history, and not repeating it. Neuroprotection for acute ischemic stroke: From review to preview

Grupke, Stephen, Hall, Jason, Dobbs, Michael, Bix, Gregory J., Fraser, Justin F.

Journal:

Clinical Neurology and Neurosurgery

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

22

Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation

Jullienne, Amandine, Roberts, Jill M, Pop, Viorela, Paul Murphy, M, Head, Elizabeth, Bix, Gregory J, Badaut, Jérôme

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2014

Language:

english

File:

PDF, 650 KB

english, 2014

23

Brain endothelial cell specific integrins and ischemic stroke

Guell, Kathleen, Bix, Gregory J

Journal:

Expert Review of Neurotherapeutics

Year:

2014

Language:

english

File:

PDF, 305 KB

english, 2014

24

Enhanced Susceptibility of Ago1/3 Double-Null Mice to Influenza A Virus Infection

Van Stry, Melanie, Oguin, Thomas H., Cheloufi, Sihem, Vogel, Peter, Watanabe, Makiko, Pillai, Meenu R., Dash, Pradyot, Thomas, Paul G., Hannon, Gregory J., Bix, Mark

Journal:

Journal of Virology

Year:

2012

Language:

english

File:

PDF, 2.17 MB

english, 2012

25

The potential role of perlecan domain V as novel therapy in vascular dementia

Marcelo, Aileen, Bix, Gregory

Journal:

Metabolic Brain Disease

Year:

2015

Language:

english

File:

PDF, 214 KB

english, 2015

26

Effects of histidine-rich glycoprotein on cerebral blood vessels

Steelman, Samantha M, Hein, Travis W, Gorman, Amy, Bix, Gregory J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2013

Language:

english

File:

PDF, 198 KB

english, 2013

27

Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke

Maniskas, Michael E, Roberts, Jill M, Aron, Ishi, Fraser, Justin F, Bix, Gregory J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 669 KB

english, 2015

28

Mice deficient in endothelial α5 integrin are profoundly resistant to experimental ischemic stroke

Roberts, Jill, de Hoog, Leon, Bix, Gregory J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

29

IL-1alpha induces angiogenesis in brain endothelial cells in vitro : implications for brain angiogenesis after acute injury

Salmeron, Kathleen, Aihara, Takuma, Redondo-Castro, Elena, Pinteaux, Emmanuel, Bix, Gregory

Journal:

Journal of Neurochemistry

Year:

2016

Language:

english

File:

PDF, 624 KB

english, 2016

30

Endorepellin Causes Endothelial Cell Disassembly of Actin Cytoskeleton and Focal Adhesions through α2β1 Integrin

Gregory Bix, Jian Fu, Eva M. Gonzalez, Laura Macro, Amy Barker, Shelly Campbell, Mary M. Zutter, Samuel A. Santoro, Jiyeun K. Kim, Magnus Höök, Charles C. Reed and Renato V. Iozzo

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 4.72 MB

english, 2004

31

Platelet-activating factor produces neuronal growth cone collapse

Clark, Gary D., McNeil, Robert S., Bix, Gregory J., Swann, John W.

Journal:

Year:

1995

File:

PDF, 604 KB

1995

32

Perlecan Domain V Inhibits Amyloid-β Induced Activation of the α2β1 Integrin-Mediated Neurotoxic Signaling Cascade

Parham, Christi L., Shaw, Courtney, Auckland, Lisa D., Dickeson, S. Kent, Griswold-Prenner, Irene, Bix, Gregory

Journal:

Journal of Alzheimer's Disease

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

33

Correcting the Trajectory of Stroke Therapeutic Research

Pennypacker, Keith R., Bix, Gregory, Fraser, Justin F.

Journal:

Translational Stroke Research

Year:

2017

Language:

english

File:

PDF, 221 KB

english, 2017

34

Intra-arterial nitroglycerin as directed acute treatment in experimental ischemic stroke

Maniskas, Michael E, Roberts, Jill M, Trueman, Rebecca, Learoyd, Annastazia E, Gorman, Amanda, Fraser, Justin F, Bix, Gregory J

Journal:

Journal of NeuroInterventional Surgery

Year:

2016

Language:

english

File:

PDF, 537 KB

english, 2016

35

Intra-arterial verapamil post-thrombectomy is feasible, safe, and neuroprotective in stroke

Fraser, Justin F, Maniskas, Michael, Trout, Amanda, Lukins, Doug, Parker, Lindsey, Stafford, W Lane, Alhajeri, Abdulnasser, Roberts, Jill, Bix, Gregory J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2017

Language:

english

File:

PDF, 875 KB

english, 2017

36

Linking Atrial Fibrillation with Alzheimer’s Disease: Epidemiological, Pathological, and Mechanistic Evidence

Ihara, Masafumi, Washida, Kazuo, Bix, Gregory

Journal:

Journal of Alzheimer's Disease

Year:

2018

Language:

english

File:

PDF, 445 KB

english, 2018

37

Uncovering the Rosetta Stone: Report from the First Annual Conference on Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical

Bix, Gregory J., Fraser, Justin F., Mack, William J., Carmichael, S. Thomas, Perez-Pinzon, Miguel, Offner, Halina, Sansing, Lauren, Bosetti, Francesca, Ayata, Cenk, Pennypacker, Keith R.

Journal:

Translational Stroke Research

Year:

2018

Language:

english

File:

PDF, 820 KB

english, 2018

38

Perlecan and the Blood-Brain Barrier: Beneficial Proteolysis?

Roberts, Jill, Kahle, Michael P., Bix, Gregory J.

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 759 KB

english, 2012

39

Roles of integrins and extracellular matrix in stroke

Edwards, Danielle, Bix, Gregory J

Journal:

American journal of physiology. Cell physiology

Year:

2018

Language:

english

File:

PDF, 609 KB

english, 2018

40

Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity

Kant, Ravi, Halder, Sebok K., Bix, Gregory J., Milner, Richard

Journal:

Acta Neuropathologica Communications

Year:

2019

File:

PDF, 6.58 MB

2019

41

Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity

Kant, Ravi, Halder, Sebok K., Bix, Gregory J., Milner, Richard

Journal:

Acta Neuropathologica Communications

Year:

2019

Language:

english

File:

PDF, 6.58 MB

english, 2019

42

The Inflammatory Response After Ischemic Stroke: Targeting β2 and β1 Integrins

Edwards, Danielle N., Bix, Gregory J.

Journal:

Frontiers in Neuroscience

Year:

2019

Language:

english

File:

PDF, 902 KB

english, 2019

43

Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic stroke

Edwards, Danielle N, Salmeron, Kathleen, Lukins, Douglas E, Trout, Amanda L, Fraser, Justin F, Bix, Gregory J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2019

Language:

english

File:

PDF, 2.29 MB

english, 2019

44

Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic stroke

Edwards, Danielle N, Salmeron, Kathleen, Lukins, Douglas E, Trout, Amanda L, Fraser, Justin F, Bix, Gregory J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2019

File:

PDF, 2.29 MB

2019

45

Biomarker Application for Precision Medicine in Stroke

Simpkins, Alexis N., Janowski, Miroslaw, Oz, Helieh S., Roberts, Jill, Bix, Gregory, Doré, Sylvain, Stowe, Ann M.

Journal:

Translational Stroke Research

Year:

2019

File:

PDF, 680 KB

2019

46

Evaluation of Patients with High National Institutes of Health Stroke Scale as Thrombectomy Candidates Using the Kentucky Appalachian Stroke Registry

Grewal, Parneet, Dobbs, Michael R., Pennypacker, Keith, Kryscio, Richard J., Kitzman, Patrick, Wolfe, Marc, Elkins, Kelley, Bix, Gregory J., Fraser, Justin F.

Journal:

Cerebrovascular Diseases

Year:

2019

File:

PDF, 207 KB

2019

47

Review of Alterations in Perlecan-Associated Vascular Risk Factors in Dementia

Trout, Amanda L., Rutkai, Ibolya, Biose, Ifechukwude J., Bix, Gregory J.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 274 KB

2020

48

Neuroinflammation and fibrosis in stroke: The good, the bad and the ugly

Amruta, Narayanappa, Rahman, Abir, Pinteaux, Emmanuel, Bix, Gregory

Journal:

Journal of Neuroimmunology

Year:

2020

File:

PDF, 891 KB

2020

49

Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney

Dalmasso, Carolina, Chade, Alejandro R., Mendez, Mariela, Giani, Jorge F., Bix, Gregory J., Chen, Kuey C., Loria, Analia S.

Journal:

Frontiers in Physiology

Year:

2020

File:

PDF, 3.60 MB

2020

50

Platelet-Activating Factor Receptor Stimulation Disrupts Neuronal Migration In Vitro

Bix, Gregory J., Clark, Gary D.

Journal:

Journal of Neuroscience

Year:

1998

File:

PDF, 4.46 MB

1998

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